# Create new substance in unity
**URL:** https://discourse.kitware.com/t/create-new-substance-in-unity/959
**Category:** Pulse Physiology Engine
**Created:** [January 11, 2023, 11:40pm UTC](https://discourse.kitware.com/t/create-new-substance-in-unity/959 "2023-01-11T23:40:07Z")
**Posts on this page:** 3
**Page:** 1
### Author:  [@Marcello\_Vecchio](https://discourse.kitware.com/u/Marcello_Vecchio)
#### Post date: [January 11, 2023, 11:40pm UTC](https://discourse.kitware.com/t/create-new-substance-in-unity/959/1 "2023-01-11T23:40:07Z")
Hello, I’m trying to create a new substance and importing it in unity but I can’t succeed.
I created the Atropine.json and stored it in Data/substances, but when I try to call it from a script unity crashes.
What am I doing wrong?
The method I am using to call it from the script is the following
> SESubstanceBolus bo = new SESubstanceBolus();
> bo.SetSubstance(“Atropine”);
> bo.GetConcentration().SetValue(50, MassPerVolumeUnit.mg\_Per\_mL);
> bo.GetDose().SetValue(1, VolumeUnit.mL);
> bo.SetAdminRoute(eSubstanceAdministration\_Route.Intravenous);
> driver.engine.ProcessAction(bo);
All other standard substances work while being called this way, only new .json can’t be opened.
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### Author:  [@abray](https://discourse.kitware.com/u/abray)
#### Post date: [January 12, 2023, 12:06am UTC](https://discourse.kitware.com/t/create-new-substance-in-unity/959/2 "2023-01-12T00:06:26Z")
If you are initializing the engine by loading a state file, that new substance needs to be in the state file
If you are initializing the engine by stabilizing to a patient configuration, that should work
Which are you doing?
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### Author:  [@Marcello\_Vecchio](https://discourse.kitware.com/u/Marcello_Vecchio)
#### Post date: [January 13, 2023, 11:25pm UTC](https://discourse.kitware.com/t/create-new-substance-in-unity/959/3 "2023-01-13T23:25:41Z")
I was loading a state file without putting it inside. Thank you