# Induce Ketoacidosis Event

**URL:** https://discourse.kitware.com/t/induce-ketoacidosis-event/1096
**Category:** Pulse Physiology Engine
**Created:** [August 31, 2023, 4:04pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096 "2023-08-31T16:04:42Z")
**Posts on this page:** 6
**Page:** 1

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### Author: ![JBengey](https://discourse.kitware.com/letter_avatar_proxy/v4/letter/j/ac91a4/32.png) [@JBengey](https://discourse.kitware.com/u/JBengey)
#### Post date: [August 31, 2023, 4:04pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/1 "2023-08-31T16:04:42Z")

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Hi,

I see there is a built-in event for the ketoacidosis condition,

I wondered what pulse action or pulse condition combination could be used to directly trigger/cause this to develop?

Thanks

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### Author: ![abray](https://discourse.kitware.com/user_avatar/discourse.kitware.com/abray/32/12_2.png) [@abray](https://discourse.kitware.com/u/abray)
#### Post date: [August 31, 2023, 4:12pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/2 "2023-08-31T16:12:01Z")

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Doing a quick search through the code base, and it looks like we have it listed as a possible event, but it is currently not set anywhere in the engine. We probably put that in there to support it in future development of a diabetes model (Which never came to fruition)

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### Author: ![JBengey](https://discourse.kitware.com/letter_avatar_proxy/v4/letter/j/ac91a4/32.png) [@JBengey](https://discourse.kitware.com/u/JBengey)
#### Post date: [August 31, 2023, 4:20pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/3 "2023-08-31T16:20:09Z")

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Ahh damn that is unfortunate to hear!

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### Author: ![JBengey](https://discourse.kitware.com/letter_avatar_proxy/v4/letter/j/ac91a4/32.png) [@JBengey](https://discourse.kitware.com/u/JBengey)
#### Post date: [September 1, 2023, 8:49am UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/4 "2023-09-01T08:49:30Z")

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Would modifying the “KetoneProductionRate” on a patient state drive any expected changes? or is this value just a placeholder?

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### Author: ![abray](https://discourse.kitware.com/user_avatar/discourse.kitware.com/abray/32/12_2.png) [@abray](https://discourse.kitware.com/u/abray)
#### Post date: [September 1, 2023, 12:10pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/5 "2023-09-01T12:10:54Z")

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No, its still a place holder  
Currently we are only using [Ketone bounds here](https://gitlab.kitware.com/physiology/engine/-/blob/stable/src/cpp/engine/common/system/physiology/TissueModel.cpp?ref_type=heads#L775)  
They are just not yet integrated fully into our substance model

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### Author: ![JBengey](https://discourse.kitware.com/letter_avatar_proxy/v4/letter/j/ac91a4/32.png) [@JBengey](https://discourse.kitware.com/u/JBengey)
#### Post date: [September 1, 2023, 12:24pm UTC](https://discourse.kitware.com/t/induce-ketoacidosis-event/1096/6 "2023-09-01T12:24:07Z")

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Got it - thanks alot.