The Simulation Modeling Toolkit (https://smtk.org/) is a set of libraries for simulation pre-processing. You can process geometric models, discretizations of those models (meshes), add attributes like boundary conditions, write simulation input decks, and even submit jobs.

The Pulse Physiology engine is a C++ library that simulates human physiology that will drive medical education, research, and training technologies.

iMSTK (http://www.imstk.org/) is a free & open source software toolkit written in C++ that aids rapid prototyping of interactive multi-modal surgical simulations.

SENSEI (https://sensei-insitu.org) is a framework that lets large-scale simulations to provide their state to analysis, visualization, and I/O tasks in situ—obviating the need for large output files.

Computational Model Builder (https://computationalmodelbuilder.org/) is a suite of applications built on ParaView and SMTK to help you prepare and submit simulations.

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